When my model is done , I like to unwrap every part of my model before starting with Zbrush. A cool trick: I like to unwrap the pieces with UvLayout and Unfold 3d.
Darkness Monster Body UV's Unwrap
The important thing to remember about the Uv's, is to make sure every square on the character is equal. This step makes the texturing part easier. If you work like that, no texture scaling will be nessesary after this step.
Darkness Monster ZBrush
Every detail is made in Zbruh with different kind of alpha and brush techniques. It is also possible to extract Displacement maps, Normal Maps and Cavity maps.